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Early intervention for adolescents at high risk for the development of bipolar disorder: pilot study of Interpersonal and Social Rhythm Therapy (IPSRT).

Identifieur interne : 003212 ( Main/Exploration ); précédent : 003211; suivant : 003213

Early intervention for adolescents at high risk for the development of bipolar disorder: pilot study of Interpersonal and Social Rhythm Therapy (IPSRT).

Auteurs : Tina R. Goldstein ; Rachael Fersch-Podrat ; David A. Axelson ; Alison Gilbert ; Stefanie A. Hlastala ; Boris Birmaher ; Ellen Frank

Source :

RBID : pubmed:24377402

Descripteurs français

English descriptors

Abstract

Interpersonal and Social Rhythm Therapy (IPSRT) delays bipolar disorder (BP) recurrence in adults by stabilizing daily routines and sleep/wake cycles. Because adolescence is a key developmental stage for illness onset and altered social and sleep patterns, this period may prove optimal for intervention with adolescents at-risk for BP. We describe a treatment development trial of IPSRT for adolescents at-risk for BP by virtue of a positive family history. Adolescents with a first-degree relative with BP were evaluated for Axis I psychopathology via semistructured interview, and relatives' BP diagnoses were confirmed via record review. IPSRT consisted of 12 sessions delivered over 6 months. Outcome variables including sleep, mood symptoms, and functioning were assessed via clinician interview and self-/parent-report at pretreatment, 3 months, and posttreatment (6 months). Thirteen adolescents attended at least one IPSRT session. Half of the sample denied Axis I psychopathology at intake; the remainder met criteria for a range of internalizing and externalizing disorders. Families reported high satisfaction with IPSRT, yet, on average, participants attended about half of scheduled sessions. Missed sessions were primarily associated with parental BP illness severity. Data indicate significant change in select sleep/circadian patterns (i.e., less weekend sleeping in and oversleeping) with treatment. Preliminary data suggest the IPSRT focus on stabilizing daily rhythms and interpersonal relationships may be beneficial for adolescents at-risk for BP. Controlled trials with longitudinal follow-up are needed to examine whether early intervention for at-risk youth helps prevent or delay disorder.

DOI: 10.1037/a0034396
PubMed: 24377402


Affiliations:


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<term>Bipolar Disorder (psychology)</term>
<term>Bipolar Disorder (therapy)</term>
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<term>Genetic Predisposition to Disease</term>
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<term>Internal-External Control</term>
<term>Interpersonal Relations</term>
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<term>Patient Education as Topic</term>
<term>Personality Assessment</term>
<term>Pilot Projects</term>
<term>Psychotherapy (methods)</term>
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<term>Social Stigma</term>
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<term>Facteurs de risque</term>
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<term>Humains</term>
<term>Intervention médicale précoce</term>
<term>Mâle</term>
<term>Projets pilotes</term>
<term>Prédisposition génétique à une maladie</term>
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<term>Psychothérapie ()</term>
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<term>Stigmate social</term>
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<term>Trouble bipolaire (diagnostic)</term>
<term>Trouble bipolaire (génétique)</term>
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<term>Troubles chronobiologiques (diagnostic)</term>
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<term>Troubles chronobiologiques (psychologie)</term>
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<div type="abstract" xml:lang="en">Interpersonal and Social Rhythm Therapy (IPSRT) delays bipolar disorder (BP) recurrence in adults by stabilizing daily routines and sleep/wake cycles. Because adolescence is a key developmental stage for illness onset and altered social and sleep patterns, this period may prove optimal for intervention with adolescents at-risk for BP. We describe a treatment development trial of IPSRT for adolescents at-risk for BP by virtue of a positive family history. Adolescents with a first-degree relative with BP were evaluated for Axis I psychopathology via semistructured interview, and relatives' BP diagnoses were confirmed via record review. IPSRT consisted of 12 sessions delivered over 6 months. Outcome variables including sleep, mood symptoms, and functioning were assessed via clinician interview and self-/parent-report at pretreatment, 3 months, and posttreatment (6 months). Thirteen adolescents attended at least one IPSRT session. Half of the sample denied Axis I psychopathology at intake; the remainder met criteria for a range of internalizing and externalizing disorders. Families reported high satisfaction with IPSRT, yet, on average, participants attended about half of scheduled sessions. Missed sessions were primarily associated with parental BP illness severity. Data indicate significant change in select sleep/circadian patterns (i.e., less weekend sleeping in and oversleeping) with treatment. Preliminary data suggest the IPSRT focus on stabilizing daily rhythms and interpersonal relationships may be beneficial for adolescents at-risk for BP. Controlled trials with longitudinal follow-up are needed to examine whether early intervention for at-risk youth helps prevent or delay disorder.</div>
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<name sortKey="Fersch Podrat, Rachael" sort="Fersch Podrat, Rachael" uniqKey="Fersch Podrat R" first="Rachael" last="Fersch-Podrat">Rachael Fersch-Podrat</name>
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